Abstract

The emergence of natural polymers like gums and mucilages in drug delivery systems has curbed the rampant use of the synthetic materials for therapeutic purposes. Natural excipients offered advantages such as non-toxicity, less cost and abundantly availablity. Aqueous solubility of natural excipients plays an important role in their selection for designing immediate, controlled or sustained release formulations. This review article provide an overview of natural gum, polymers and mucilages as excipients in dosage forms as well as novel drug delivery systems.These recent investigations have provided ample evidences that these natural gums and mucilages like Gellan Gum,Gum Acacia,Locust bean gum could efficaciously deliver therapeutics to the diseased site without exerting any significant adverse effects on the normal cells. Hencefoth these natural polymers are endowed with the ability to function as like green emissaries for the transport of essential therapeutic agents which in turn will help in restraining the belligerence of different grave diseases like cancer.

Highlights

  • Graphical AbstractThe emergence of natural polymers like gums and mucilages in drug delivery systems has curbed the rampant use of the synthetic materials for therapeutic purposes

  • Natural polymers and their semi-synthetic derivatives gained popularity in development of novel drug delivery systems

  • The results showed different drug release mechanisms from ternary mixture based on the concentration of kappa-carrageenan used

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Summary

Graphical Abstract

The emergence of natural polymers like gums and mucilages in drug delivery systems has curbed the rampant use of the synthetic materials for therapeutic purposes. This review article provides an overview of natural gum, polymers and MOL2NET, 2020, 6, ISSN: 2624-5078 2 http://sciforum.net/conference/mol2net-06 mucilages as excipients in dosage forms as well as novel drug delivery systems. These recent investigations have provided ample evidences that these natural gums and mucilages like Gellan Gum, Gum Acacia, and Locust bean gum could efficaciously deliver therapeutics to the diseased site without exerting any significant adverse effects on the normal cells.

Introduction
Research performed on natural polymers
Findings
Conclusions
Full Text
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