Abstract

We read with interest the paper by Turnbridge et al. in the journal, on the clinical management of chickenpox in adults. 1 Tunbridge A.J. Breuer J. Jeffery K.J. Chickenpox in adults – clinical management. J Infect. 2008 Aug; 57: 95-102 Abstract Full Text Full Text PDF PubMed Scopus (64) Google Scholar Chickenpox is a significant cause of morbidity and mortality in Sri Lanka as it predominantly affects adults. We previously described the association of clinical disease severity with viral loads and cellular immune responses in Sri Lankan adults with chickenpox. 2 Malavige G.N. Jones L. Kamaladasa S.D. Wijewickrama A. Seneviratne S.L. Black A.P. et al. Viral load, clinical disease severity and cellular immune responses in primary varicella zoster virus infection in Sri Lanka. PLoS One. 2008; 3: e3789 Crossref PubMed Scopus (42) Google Scholar We wish to highlight the possible role of natural killer cells in the control of virus replication in patients with acute infection.

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