Natural feruloyl monoglyceride macrocycles as protecting factors against free-radical damage of lipidic membranes

Abstract

Nine novel natural feruloyl monoglyceride (MGs) macrocycles have been isolated from the leaves of Carex distachya, an herbaceous plant growing in the Mediterranean maquis. All the structures have been elucidated on the basis of their spectroscopic features, especially two-dimensional NMR (DQ-COSY, TOCSY, NOESY, ROESY, HSQC, HMBC, HSQC–TOCSY) and ESI-MS. All the compounds have been assayed as protecting factors against the radical damage of the lipids by using different antioxidant tests.