Abstract

Researchers at the Rockefeller University in New York, USA and the Institute for Human Genetics and Biochemistry in Switzerland have discovered HIV-fighting antibodies as a component of the body's innate immune system. These antibodies defend against infection with HIV by binding to the HIV protein Tat. The researchers suspect that a person infected with HIV develops full-blown AIDS as the body begins to lose its innate immunity to the virus. Therefore, if adequate levels of the innate antibodies could be restored, it might be possible to prevent HIV-related illness. This discovery might open the door to a new approach to the treatment of HIV infection. Exp. Hematol. (2001) 29, 1004–1009 SW

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