Abstract
A benzophenone glycoside has been isolated from Davallia solida. Its structure was elucidated by chemical and spectral means as 4- 0-β- d-glucopyranosyl-2,6,4′-trihydroxybenzophenone. It bound with moderate affinity to the purified C-terminal cytosolic domain of P-glycoprotein, but the binding affinity was 6- to 10-fold increased for its aglycone derivative and other related benzophenones.
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