Abstract

Nacartocin, a synthetic analogue of oxytocin, [2-L-p-phenylalanine]deamino-6-carba-oxytocin has a specific natriuretic effect in cats. The doses of 0.05-10 micrograms/kg b.w. (0.05-10 nmols/kg) of Nacartocin applied i.v. caused a several fold increase in the excretion of sodium, while the excretion of kalium was only slightly enhanced.

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