Abstract
The natriuretic peptides are a family of circulating peptides that play an important role in the regulation of extracellular fluid volume and blood pressure. These peptides induce natriuresis, diuresis, and vasodilatation and specifically act to counter the effects of the renin-angiotensin-aldosterone system.1-3 The cardiac members of this family are the atrial or A-type natriuretic peptide (ANP) and the B-type natriuretic peptide (BNP). ANP is secreted primarily from the cardiac atria in response to increased left and right atrial pressure as well as volume loads, whereas BNP is secreted primarily from the ventricles in response to increased left and right ventricular pressure and volume loads.
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