Abstract
Seroprevalence surveys provide estimates of the extent of SARS-CoV-2 infections in the population, regardless of disease severity and test availability. In Mexico in 2020, COVID-19 cases reached a maximum in July and December. We aimed to estimate the national and regional seroprevalence of SARS-CoV-2 antibodies across demographic and socioeconomic groups in Mexico after the first wave, from August to November 2020. We used nationally representative survey data including 9,640 blood samples. Seroprevalence was estimated by socioeconomic and demographic characteristics, adjusting by the sensitivity and specificity of the immunoassay test. The national seroprevalence of SARS-CoV-2 antibodies was 24.9% (95%CI 22.2, 26.7), being lower for adults 60 years and older. We found higher seroprevalence among urban and metropolitan areas, low socioeconomic status, low education and workers. Among seropositive people, 67.3% were asymptomatic. Social distancing, lockdown measures and vaccination programs need to consider that vulnerable groups are more exposed to the virus and unable to comply with lockdown measures.
Highlights
Seroprevalence surveys provide estimates of the extent of SARS-CoV-2 infections in the population, regardless of disease severity and test availability
We aimed to estimate the prevalence of SARS-CoV-2 antibodies in Mexico using a nationally representative sample
Seroprevalence was higher among workers, low socioeconomic groups, low education and urban and metropolitan areas among adults
Summary
Seroprevalence surveys provide estimates of the extent of SARS-CoV-2 infections in the population, regardless of disease severity and test availability. We aimed to estimate the national and regional seroprevalence of SARS-CoV-2 antibodies across demographic and socioeconomic groups in Mexico after the first wave, from August to November 2020. Representative SARS-CoV-2 seroprevalence surveys estimate the extent of infection in the population independently of severity and test availability[1]. Prior studies in Mexico have suggested that COVID-19 infections could be higher among low socioeconomic groups[9]. In response to the emergency, a nationally representative serosurvey was implemented between August and November just after the first wave subsided Using data from this survey, we aimed to estimate the seroprevalence of SARS-CoV-2 antibodies in Mexico at the national and regional level. We explored the demographic and socioeconomic characteristics associated with seropositivity
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