Abstract
National Cancer Institute and Imaging-Intersecting Scientific Opportunity with Clinical Need.
Highlights
A critical technology in the fight against cancer is in vivo imaging
The focus is on functional imaging, emphasizing the physiological, cellular, or molecular processes in living tissues, as they take place. (As Richard Klausner noted when he was the National Cancer Institute (NCI) Director, imaging used to be “location, location, location,” in the future it will be “information, information, information.”)
Investigators can apply for grants from the Exploratory/Developmental Grants for Diagnostic Cancer Imaging initiative, or the Phased Innovation Award (R21/R33) Program
Summary
A critical technology in the fight against cancer is in vivo imaging. Detection through imaging of the molecular changes associated with a tumor cell will improve our ability to detect and stage tumors, select appropriate treatments, monitor the effectiveness of treatment, and determine prognosis. The NCI has developed programs to move imaging into roles such as determining the pathogenesis of risk, identifying preclinical disease, enabling drug discovery, and facilitating tumor-selective image-guided interventions (http://cip.cancer.gov). The In Vivo Cellular and Molecular Imaging Centers bring together a variety of investigators to develop molecular (functional) imaging methods and techniques for animals and humans.
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