Abstract

Amyloidosis results from the deposition of amyloid proteins in organs and tissues. Localized amyloidosis in the head and neck is a rare and benign process. Amyloidosis involving the nasopharynx or neck is even rarer. In this paper, a case of localized amyloidosis of the nasopharynx and neck mimicking nasopharyngeal carcinoma with neck metastasis was reported with a literature review. The only complaint was nasal stuffiness. The diagnosis was made through nasopharyngeal biopsy and fine needle aspiration biopsy (FNAB) of the neck masses. Subsequent nasopharyngeal curettage was undertaken. No further treatment was given, and there was no evidence of disease in the 20th postoperative month. Amyloidosis, although rare, should be considered in the differential diagnosis of head and neck masses.

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