Abstract
Linear IgA disease (LAD) is rare and there are only a few cases reported where its lesions were limited to the oral mucosa. Eosinophilic granulomatosis with polyangiitis (EGPA) is also a rare multisystemic disease. Therefore, the occurrence of LAD and EGPA in the same patient is very rare. Here we report the oral manifestations of a case of a 24-year-old female who first presented with idiopathic thrombocytopenic purpura (ITP) and was treated with dapsone, with LAD occurring later. Over the next 6 years, this patient developed hypothyroidism, asthma, eosinophilia, glaucoma, abnormal menstruation, arthritis, glomerulonephritis and respiratory tract involvement. Finally, EGPA was diagnosed by her physicians. This is the first case report of LAD and EGPA that radiographically showed the development of generalized severe alveolar bone loss and internal root resorption of the maxillary right second premolar between the first visit and a 2-year follow-up.
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