Abstract

Mucocutaneous ulcers mimicking Behcet disease as the initial presentations of nasal-type extranodal natural killer (NK)/T-cell lymphoma (ENKTCL) are rare. We report a case of 53-year-old male with initial presentations of multiple mucocutaneous ulcers in the oral and genital areas. Serology tests for autoimmune disease (e.g. anti-nuclear antibody) were all negative except for expression of HLA-B51. Biopsy of buccal mucosa showed leukocytoclastic vasculitis. The follow-up chest plain films showed multiple lung nodules, biopsy of which revealed nasal-type ENKTCL. The patient received systemic chemotherapy as soon as the diagnosis was confirmed but died of lymphoma progression and pneumonia within one month of diagnosis. Early diagnosis and treatment are important due to ENKTCL's highly aggressive clinical course.

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