Abstract
Nasal symptoms in patients with NSAID hypersensitivity
Highlights
Hypersensitivity to aspirin/acetylsalicylic acid (ASA) and other nonsteroidal anti-inflammatory drugs (NSAID) has a prevalence of 1-2% in the general population [1]
It is recommended that patients with NSAID hypersensitivity are screened for sino-nasal symptoms and referred for ENT evaluation
chronic rhinosinusitis (CRS) was diagnosed based on symptoms and nasal rhinoscopy according to the European Position Paper on Rhinosinusitis and Nasal Polyps 2012 (EPOS)
Summary
Hypersensitivity to aspirin/acetylsalicylic acid (ASA) and other nonsteroidal anti-inflammatory drugs (NSAID) has a prevalence of 1-2% in the general population [1]. It manifests with a variety of reactions involving skin, respiratory tract and anaphylaxis. According to the classification system the majority of patient with CRS and NSAID hypersensitivity will be classified as having NSAIDs-exacerbated respiratory disease (NERD). In NERD the hypersensitivity reaction manifests primarily as bronchial obstruction, dyspnea, and nasal congestion/ rhinorrhea in patients with an underlying chronic airway respiratory disease (asthma/rhinosinusitis). Among patients with asthma and chronic rhinosinusitis (CRS) with nasal polyps the prevalence of NSAID hypersensitivity is 20 to 42% [4, 5]. The aim of this study was to estimate the prevalence of chronic rhinosinusitis in patients with NSAID hypersensitivity and to evaluate QoL and the need of ENT intervention
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
