Abstract
Recent studies in aspirin-exacerbated respiratory disease (AERD) demonstrated inflammatory heterogeneity. Using cytokine profiling of nasal mucus collected during functional endoscopic sinus surgery (FESS) from 30 patients with AERD, we previously identified three inflammatory clusters: overall low (cluster 1), high type-2 (cluster 2), and high type-1/3 (cluster 3). We hypothesized that nasal inflammatory profile at the time of surgery would impact post-operative clinical outcomes.
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