Narrow-band imaging system with magnifying endoscopy in differentiating colorectai neoplasms from non-neoplasms

Abstract

Objective To observe the meshed capillary pattern （CP） on the surface of colorectal lesions by narrow-band imaging system with magnifying endoscopy （NBI-ME）, and to distinguish neoplasm from non-neoplasm by the change of capillary patterns. Methods A total of 144 eolorectal lesions in 102 patients detected by conventional eolonoscopy were evaluated by NBI-ME to observe the CP on surface, and by staining magnifying colonoscopy to observe the pit pattern. Results All lesions were resected endoscopically （129/144） or by surgery （15/144）, and the pathological evaluation diagnosed 30 cases of non-neoplasm （including 20 cases of hyperproliferative polyps and 10 of inflammatory polyps） and 114 cases of neoplasm （including 95 cases of adenoma and 19 cases of adenocarcinoma）. The diagnostic accuracy rate, sensitivity and specificity of conventional colonoscopy were 75.7% , 85. 1% and 40. 0% , respectively, which were significantly lower than those of NBI-ME and staining magnifying colonoscopy （ P 〈 0. 005 ） , while there was no significant difference between NBI-ME and staining magnifying colonoscopy. The CP of type Ⅰ , Ⅱ , Ⅳand Ⅵa were totally correspondent with pit pattern of type Ⅰ , Ⅱ , ⅣandⅤ1 Conclusion NBI-ME findings of colorectal lesions correlated with those of staining magnifying colonoscopy. These two techniques are both helpful in differentiating colorectal neoplasms from non-neoplasms. Key words: Colorectal neoplasm ; Endoscopy ; Narrow-band imaging system ; Magnifying endoscopy; Pit pattern