Abstract

Background: Comorbid Posttraumatic Stress Disorder (PTSD) increases the already high symptom burden of patients with Borderline Personality Disorder (BPD). As the gold standard for BPD treatment, Dialectical Behavior Therapy (DBT), does not focus on PTSD, other treatment approaches are needed. Narrative Exposure Therapy (NET) was designed to address multiple traumatic events and may be especially useful in this patient group. The aim of the present study was to determine the efficacy of NET compared to DBT based treatment (DBT-bt) in a randomized controlled trial.Methods: Female patients (n = 60) with BPD and comorbid PTSD were randomized to either a 10-week residential NET or DBT-bt. The primary outcome was change in PTSD severity as assessed by the Clinician Administered PTSD Scale (CAPS). Mixed linear models as well as reliable change, remission, and response rates were used to compare improvement across treatment groups.Results: Mixed linear model showed that patients in both treatments improved significantly over time across all outcome measures. This improvement was not more pronounced in NET (no significant time × type of treatment effect). However, NET resulted in a higher remission rate as compared to DBT-bt. PTSD remission was accompanied by BPD remission in all cases.Conclusions: This study shows the value of trauma-focused therapy in patients with BPD and PTSD for recovery in both disorders. To shorten the duration of both illnesses as much as possible, future studies should focus on the factors predicting treatment success and enabling patients to benefit from trauma-focused treatment as soon as possible.Trial registration: ClinicalTrials.gov, identifier: NCT02517723.

Highlights

  • About half of all patients with borderline personality disorder (BPD) suffer from comorbid posttraumatic stress disorder [Posttraumatic Stress Disorder (PTSD); [1]]

  • This study shows the value of trauma-focused therapy in patients with BPD and PTSD for recovery in both disorders

  • We aimed to evaluate Narrative Exposure Therapy (NET) in severely ill patients with both BPD and PTSD on the recovery of primarily PTSD and BPD compared to Dialectical Behavior Therapy (DBT) based treatment in a naturalistic residential setting including a 12-months follow-up

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Summary

Introduction

About half of all patients with borderline personality disorder (BPD) suffer from comorbid posttraumatic stress disorder [PTSD; [1]]. For the treatment of PTSD, exposure-based cognitive-behavioral treatment programs are most effective [3]. For a long time there were reservations about the safety of exposure therapy in patient groups that exhibit high levels of dysfunctional behaviors, such as BPD [4]. Dialectical Behavior Therapy [DBT; [5]], the treatment program that has demonstrated its effectiveness in BPD most often, was not found to be sufficiently effective on PTSD symptomatology in patients with BPD and PTSD [6]. Comorbid Posttraumatic Stress Disorder (PTSD) increases the already high symptom burden of patients with Borderline Personality Disorder (BPD). As the gold standard for BPD treatment, Dialectical Behavior Therapy (DBT), does not focus on PTSD, other treatment approaches are needed. The aim of the present study was to determine the efficacy of NET compared to DBT based treatment (DBT-bt) in a randomized controlled trial

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