Abstract
The reaction of indole (2-methylindole) with 1,5-, 1,6-, and 1,8-naphthyridines at 20‡C, in the presence of benzoyl chloride, leads to the preferential formation of dihydro structures with one indolyl substituent at the α-position to the hetero atom. With increase in temperature, dibenzoyl and monobenzoyl tetrahydro-substituted naphthyridines with two indolyl residues in both pyridine rings are formed besides the above compounds.
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