Abstract
Nanozymes own striking merits, including high enzyme-mimicking activity, good stability, and low cost. Due to the powerful and distinguished functions, nanozymes exhibit widespread applications in the field of biosensing and immunoassay, attracting researchers in various fields to design and engineer nanozymes. Recently, nanozymes have been innovatively used to bridge nanotechnology with analytical techniques to achieve the high sensitivity, specificity, and reproducibility. However, the applications of nanozymes in food applications are seldom reviewed. In this review, we summarize several typical nanozymes and provide a comprehensive description of the history, principles, designs, and applications of nanozyme-based analytical techniques in food contaminants detection. Based on engineering and modification of nanozymes, the food contaminants are classified and then discussed in detail via discriminating the roles of nanozymes in various analytical methods, including fluorescence, colorimetric and electrochemical assay, surface-enhanced Raman scattering, magnetic relaxing sensing, and electrochemiluminescence. Further, representative examples of nanozymes-based methods are highlighted for contaminants analysis and inhibition. Finally, the current challenges and prospects of nanozymes are discussed.
Highlights
Nanomaterials have received widespread attention in fields like chemistry, biology, environment, medicine and health, aerospace, resources and energy, and so on (Huang et al, 2019d; Wu et al, 2019a; Sun et al, 2018)
To achieve robust detection of pesticides, several analytical techniques based on nanozymes are developed and highlighted
Various nanozyme-based analytical methods have been developed to analyze food contaminants aiming at achieving good selectivity, high sensitivity, and stability
Summary
Nanomaterials have received widespread attention in fields like chemistry, biology, environment, medicine and health, aerospace, resources and energy, and so on (Huang et al, 2019d; Wu et al, 2019a; Sun et al, 2018). Nanozymes-based analytical methods are carefully discussed to prove the good detection performance, especially for food contaminants with certain limit quantity. Nanozyme-based detection techniques can greatly improve the sensitivity with specific structural properties and excellent catalytic activity.
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