Nanotechnology for Effective Epilation: Assessment of the Application of a Protease-Containing Microemulsion

Abstract

Background: Epilation is a very effective way to remove unwanted hair because of its long-lasting effects. However, there are some disadvantages such as pain during the procedure, the possibility of ingrown hairs and perifollicular inflammation. In the present study, we investigated whether a protease-containing post-epilation microemulsion is effective in improving epilation performance and alleviating the above problems. Methods: The application characteristics and effects of the tested microemulsion were evaluated during and after three applications in 30 female volunteers. This was conducted by measuring hair density, assessing hair strength, and evaluating the subjective experience of the volunteers using a questionnaire. Results: The measurements showed that after three applications, the apparent hair density in the axilla was reduced from 43.89 ± 12.44 hairs/cm2 to 16.67 ± 6.61 hairs/cm2 (p < 0.0001). In general, volunteers observed a reduced hair regrowth rate, resulting in longer epilation intervals, and more soothed and moisturized skin. Volunteers who previously experienced ingrown hairs or perifollicular inflammation reported the absence or improvement of these problems. Conclusions: The protease-containing microemulsion not only improves the performance of the epilation procedure, leading to less frequent epilation, but also improves possible negative effects of epilation such as ingrown hairs and perifollicular inflammation.