Nanotechnology: An avenue for combating fish parasites in aquaculture system

Abstract

The intensification of aquaculture in recent years has led to the rise of infectious fish diseases caused by bacteria, viruses, and parasites. Parasitic diseases, in particular, are widespread and have significant economic impacts globally. Protozoan parasites like Ichthyophthirius multifiliis and Trichodina sp., myxozoans (cnidarians), monogeneans like Dactylogyrus sp. and Gyrodactylus sp., and crustacean parasites like Argulus sp. and Lernaea cyprinacea primarily cause these diseases. Despite advancements and new technologies aimed at understanding and treating these diseases, parasites remain a major health challenge in aquaculture. Traditional antiparasitic agents face limitations, including drug resistance and negative effects on non-target organisms. Recently, nanotechnology has emerged as a novel approach in aquaculture medicine, enabling the development of effective nanoparticles against pathogenic microbes. Silver nanoparticles (AgNPs) are particularly notable for their strong antimicrobial and antiparasitic properties due to their broad mechanisms of action. Although Argulus is a highly destructive crustacean parasite that financially burdens fish farmers, applying nanoparticles to manage this infection in aquaculture is still underexplored. Therefore, this review explores recent efforts to combat parasitic diseases with AgNPs and investigates their potential parasiticidal mechanisms of action, proposing them as a novel tool that could improve the management and control of argulosis diseases. The article underscores the benefits and challenges of this technology, emphasizing its significance in fostering improved health management for sustainable aquaculture.