Abstract
Phospholipids bilayers fulfill an important role in natural joint lamellar-repulsive lubrication mechanism. Low friction between surfaces coated with negatively charged the phospholipid headgroup (–PO4-) as being due to a hydration layer. Wettability of the cartilage surface depends on the number of PLs that act as a lubricant. The cartilage can be classified as a group of intelligent material, which in the wet state has a contact angle of ~0º, and the air-dry state has a contact angle of ~104º.
Highlights
Phospholipids bilayers fulfill an important role in natural joint lamellarrepulsive lubrication mechanism [1, 2]
The cartilage can be classified as a group of intelligent material, which in the wet state has a contact angle of ~0o, and the air-dry state has a contact angle of ~104o
Wettability of the cartilage surface depends on the number of PLs that act as a lubricant [2, 10]
Summary
Phospholipids bilayers fulfill an important role in natural joint lamellarrepulsive lubrication mechanism [1, 2]. Articular cartilage (AC) is a specific type of connective tissue without blood vessels and innervation. There is hyaline cartilage 3-5mm thick in the joints, which feeds in motion based on diffusion. Figure 1A: presents an image made by electron microscopy of human knee cartilage with phospholipid bilayers adsorbed on the surface [3]. In Figure 1(B), four zones in the articular cartilage (~ 0.06) m 3-5 phospholipid bilayers, 100 m horizontally arranged collagen fibers with chondrocytes, ~ 600 m middle zone with indirectly arranged collagen, proteoglycan and chondrocytes, ~ 300 m collagen (vertical arrangement) with chondrocytes) were distinguished. The surface of the cartilage in the joint is hydrophilic, and the cartilage on the air loses its moisture and becomes hydrophobic
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