Abstract
We report the use of nanostructuredTiO2 (NST) as porous cellular adhesion interfaces for microsystems. Integrated NST films andpad arrays with sponge-like morphology were fabricated by aqueous oxidation of Tifilms followed by thermal annealing. Cell culture studies indicate significantly(t<0.02 from thestudent’s t-test) greater initial attachment of mouse fibroblast cells on porous NST than on silicondioxide and nitride films for up to 18 h seeding time. Fibroblasts seeded on NST have flatmorphology with numerous processes attaching to walls of NST. These results indicate thepotential of using NST as porous cell adhesion films and membranes for bioMEMSapplications.
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