Abstract
In this study, we compared two types of nanostructured electrodes with gold nanocolumns and flat gold electrodes by measurements with doxorubicin. Nanostructured electrodes were fabricated by electrochemical anodic oxidation followed by deposition of gold to the porous alumina. Flat gold electrodes were fabricated by physical evaporation of gold layer to the silicon substrate. All electrodes were characterized by electrochemical impedance spectroscopy and then the electrochemical determination of doxorubicin was studied by differential pulse voltammetry. The impedance spectroscopy measurements proved a bigger electroactive area for nanostructured electrodes. The gold nanocolumns have been found as an important factor in increasing of electrodes active area. This fact is very important for sensors sensitivity. Fabricated electrodes were successfully used for determination of doxorubicin.
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