Abstract

PurposeTo test the nanostructured hydroxyapatite as an augmenting material to expand the orbit after initial placement of a porous implant.MethodsNanostructured hydroxyapatite powder mixed with blood was surgically introduced in the scleral sac of 6 eviscated rabbits (Oryctolagus cuniculus europaeus) after previous placing of a porous hydroxyapatite integrated implant (proved by CT scan). CT scans were done at 1, 2 and 3 months postsurgical to demonstrate the integration of the injected material in the porous implant. The scleral sac wes removed after 3 months and histopathologic examination plus CD31 + (as a marker of neovascularization and osteosinthesis) were performed.ResultsCTscans performed at 1, 2 and 3 months postoperatively and the rapid development of CD31 + osteoclasts and vascular tissue pleade for a good integration of the new material in the previous porous hydroxyapatite implant.ConclusionsThis method can be used for enhancing the volume of a small scleral sac with a previous hidroxyapatite implant. Further studies should be performed.

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