Abstract

Biosensing devices and systems have attracted tremendous research interest in recent years, mainly due to the rapidly expanding market of wearable and portable devices for applications in clinical diagnosis and physiological monitoring. In our work, novel and unique hierarchical nanostructures were designed and synthesized to realize biosensing performance enhancement, especially the sensor stability. The nanostructured electrochemical sensors demonstrated effective enzymes immobilization and enhanced devices robustness, which is highly desirable towards stable and reliable noninvasive health monitoring. Meanwhile, scalable and printable approach was developed to integrate high performance electrochemical devices into monolithically integrated self-powered systems. The as-developed nanostructured electrochemical devices in conjunction with printable approach show great potency in fabrication of various wearable integrated self-powered devices for personalized healthcare monitoring applications.

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