Abstract
A sensitive and selective electrochemical method was developed for the determination of glutathione (GSH) in hemolysed erythrocyte using vinylferocene modified carbon nanotubes paste electrode (VFMCNTPE). The results indicate that the electrode is efficient in terms of its electrocatalytic activity for the oxidation of GSH, leading to a reduced overpotential by more than 470 mV. Also, the values of catalytic rate constant (k), and diffusion coefficient (D) for GSH were calculated. The electrocatalytic oxidation peak current of GSH showed two linear dynamic ranges with a detection limit of 0.09 μM GSH. The linear calibration ranges were obtained between 0.2–4.0 and 4.0–250.0 μM GSH using square wave voltammetry (SWV) method. The proposed method was also examined as a selective, simple and precise electrochemical sensor for the determination of GSH in real samples such as urine and hemolysed erythrocyte.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
