Abstract
Via one-step Laser Ablation process, different contributions of copper oxide nanoparticles (CuONPs) were scattered through Polyethylene Oxide (PEO)/Polyvinyl pyrrolidone (PVP) blend matrix. The obtained films were characterized via XRD and FTIR. Their micro-structural features and morphological behaviors were investigated using TEM and FESEM. The CuONPs were formed in a spherical shapes with dimensions around 50 nm in case of processing time 5.0 min, while their size was deteriorated at t = 25.0 min to be around 30 nm upon TEM micrographs. In addition, surface roughness average was enhanced from 26.0 nm at no contribution of CuONPs reaching to 37.0 nm at the highest content. The composite films displayed antibacterial activity against E. coli and S. aureus upon CuONPs contribution. The antibacterial activity jumped from no effect at no contribution of CuONPs to be around 89 ± 4% and 82 ± 3% against E. coli and S. aureus respectively at their highest contribution. Therefore, it could be seen that these films were carried out using facile method and displayed a great effectiveness through biological environment which could encourage more investigations for these compositions to be suggested for wound healing applications.
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