Abstract
Exploring secondary outputs, specifically leftover materials from steam distillation of Rosmarinus tournefortii de Noé, as agents for reducing metals introduces a novel approach to eco-friendly nanomaterial production. This concept aligns with the creation of environmentally conscious nanoparticles, showcasing potential across various fields, notably biomedicine. By utilizing R. tournefortii de Noé, successful synthesis of silver nanoparticles (AgNPs) was achieved, yielding nanoscale variations influenced by plant's by-products. Beyond structural aspects, investigating biomedical applications, focusing on antioxidant and antimicrobial properties. Consistently observing ∼94.9–97.3% scavenging inhibition in water residues at different concentrations and enhanced antimicrobial efficacy against Gram-negative and Gram-positive bacteria and Rhodotorula glutinis yeast due to these residues. Moreover, a thorough examination using density functional theory unveiled a robust interaction between silver clusters and specific biomolecules found within the residues, namely homoplantaginin, protocatechuic acid-glycoside, caffeic, and rosmarinic acids (ranging from 130.62 to 357.05 kcal/mol). These compounds notably enhance reducing efficacy of Ag + ions and contribute to the enduring stability of AgNPs (ζ values: −22.8 mV and −17.2 mV). Furthermore, the study recognizes challenges in finding alternative surface modification agents and explores intricate toxicity mechanisms of silver nanoparticles, emphasizing their interactions with inflammation. Introducing promising nanomedicine approaches involving rosmarinic acid nanoparticles for inflammatory bowel disease and rheumatoid arthritis, highlighting the potential of rosemary by-products derived compounds in innovative therapeutic interventions for diverse inflammatory conditions.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.