Abstract

Nanophotonics excels at confining light into nanoscale optical mode volumes and generating dramatically enhanced light matter interactions. These unique aspects have been unveiling a plethora of fundamentally new optical phenomena, yet a critical issue ahead for nanophotonics is the development of novel devices and applications that can take advantage of these nano-scale effects. It is expected that nanophotonics will lead to disruptive technologies in energy harvesting, quantum and integrated photonics, optical computing and including biosensing. To this end, our research is focused on the application of nanophotonics to introduce powerful biosensors that can have impact on a wide range of areas including basic research in life sciences, early disease diagnostics, safety and point-of-care testing. In particular, we exploit nanophotonics and its integration with microfluidics to address key challenges of current biosensors and develop devices that can enable label-free, ultra-sensitive, multiplexed, rapid and real-time measurements on biomolecules, pathogens and living systems. In this talk I will present some of our recent work on nanophotonic meta surfaces for biosensing and bioimaging as well as their applications in real-world settings.

Highlights

  • With the emerging new healthcare initiatives including personalized medicine, global health care and point-ofcare diagnostics, we are witnessing a paradigm shift in the way medical care is provided

  • We combine the use of smart data science tools with bioimaging based sensing architectures for achieving unprecedented performance metrics

  • I will present some of our recent work on nanophotonic metasurfaces for biosensing and bioimaging and show examples how they can be used in real-world applications [1,2,3,4,5,6,7,8,9,10,11,12,13,14]

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Summary

Introduction

With the emerging new healthcare initiatives including personalized medicine, global health care and point-ofcare diagnostics, we are witnessing a paradigm shift in the way medical care is provided These initiatives are demanding generation diagnostics and bioanalytical tools that can deliver a long list of desired specifications such as high sensitivity, multiplexing, real-time operation, and miniaturization, low-cost. We combine the use of smart data science tools with bioimaging based sensing architectures for achieving unprecedented performance metrics In this talk, I will present some of our recent work on nanophotonic metasurfaces for biosensing and bioimaging and show examples how they can be used in real-world applications [1,2,3,4,5,6,7,8,9,10,11,12,13,14]. 2.1 Mid-IR Plasmonics for Label-Free, Sensitive and Real-Time Monitoring of Biomolecular

Conformational Changes
Metasurfaces for Biosensensing and Imaging
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