Nanoparticles as a Dosage Form in Practice

Abstract

Nanoparticles belong to a modern and developing group of drug delivery systems with great potential for further future use. To pharmacotherapy, it brings a number of advantages. The combination of their size, specific properties of used excipients and a suitable drug can result in a more targeted therapy for some serious diagnoses. However, potential adverse effects are also associated with the subcellular size of the pharmaceutical form, and although research is being conducted with countless excipients and types of nanoparticles, only a small proportion of them have made it into clinical practice. This brief overview discusses these classes, it presents the basic characteristics, classification, and possible clinical use. The article also includes an up-to-date overview of representatives of individual nanoparticle drug delivery classes currently registered in the Czech Republic.