Nanoparticle Interactions: Mass Cytometry and Single‐Cell RNA‐seq Profiling of the Heterogeneity in Human Peripheral Blood Mononuclear Cells Interacting with Silver Nanoparticles (Small 21/2020)

Abstract

In article number 1907674, Tae Hyun Yoon and co-workers report complementary use of single-cell based mass cytometry and RNA-seq techniques for the analysis of the heterogeneous interaction between nanoparticles and human immune cells at a single-cell level, via the identification of various immune cell types, quantification of cell-associated nanoparticles, and observation of the changes in transcriptomic profiles and signaling protein expressions.