Abstract

By taking advantage of the high catalytic activity and high turnover frequency (TOF) of heterogeneous metal nanoparticle catalysts, continuous-flow systems, in which introduced reactants are converted into the desired product in high yield, can be realized. These continuous-flow reactors possess high compatibility with sequential continuous-flow systems, which enable multistep flow synthesis of biologically active compounds such as active pharmaceutical ingredients (APIs) and natural products.

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