Abstract
Nanoparticles and other nanomaterials are increasingly considered for use in biomedical applications such as imaging, drug delivery, and hyperthermic therapies. Thus, understanding the interaction of nanomaterials with biological systems becomes key for their safe and efficient application. It is increasingly being accepted that the surface of nanomaterials would be covered by protein corona upon their entrance to the biological medium. The biological medium will then see the achieved modified surface of nanomaterials, and therefore further cellular/tissue responses depend on the composition of corona. In this chapter, we describe the corona variations according to the physicochemical properties of nanomaterials (e.g., size, shape, surface charge, surface functional groups, and hydrophilicity/hydrophobicity). Besides the nanomaterials’ effects, the role of environment factors, such as protein source and slight temperature variations, is discussed in details.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
