Nanomolar E-selectin inhibitors: 700-fold potentiation of affinity by multivalent ligand presentation.

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTNanomolar E-Selectin Inhibitors: 700-Fold Potentiation of Affinity by Multivalent Ligand PresentationGebhard Thoma, Rudolf O. Duthaler, John L. Magnani, and John T. PattonView Author Information Novartis Pharma AG CH-4002 Basel, Switzerland GlycoTech Corporation, 14915 Broschart Road Rockville, Maryland 20850 Cite this: J. Am. Chem. Soc. 2001, 123, 41, 10113–10114Publication Date (Web):September 22, 2001Publication History Received19 June 2001Published online22 September 2001Published inissue 1 October 2001https://doi.org/10.1021/ja0164430Copyright © 2001 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views404Altmetric-Citations39LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (41 KB) Get e-AlertsSupporting Info (2)»Supporting Information Supporting Information SUBJECTS:Carbohydrates,Conjugate acid-base pairs,Inhibition,Inhibitors,Ligands Get e-Alerts