Nanoliposomes as Drug Delivery Systems for Antifungal Therapy

Abstract

Nanoliposomes are lipid bilayer nanostructures recently gaining popularity as drug delivery vehicles. Their biocompatibility, safety, high entrapment efficiency and drug release profiles have made them suitable candidates for biomedical applications. The treatment of fungal infec-tions is one of the most significantly researched fields in which nanoliposomes (NLPs) find a variety of uses. Although this topic has been referenced in several general reviews, it has never been thoroughly discussed. In our review, we give a detailed summary of the recent advance-ments made in this field, with a focus on encapsulated synthetic and natural antifungal agents for oral, parenteral, and transdermal applications, and the numerous advantages they have over con-ventional antifungal therapies, recent strategies at site-specific targeting using targeting moieties, as well as highlighting the safety concerns associated with NLP nanocarriers.