Abstract
In the era of nanotechnology, the synthesis of nanomaterials for advanced applications has grown enormously. Effective therapeutics and functionalization of effective drugs using nano-vehicles are considered highly productive and selectively necessary. Polymeric nanomaterials have shown their impact and influential role in this process. Polymeric nanomaterials in molecular science are well facilitated due to their low cytotoxic behavior, robust functionalization, and practical approach towards in vitro and in vivo therapeutics. This review highlights a brief discussion on recent techniques used in nanohydrogel designs, biomedical applications, and the applied role of nanohydrogels in the construction of advanced therapeutics. We reviewed recent studies on nanohydrogels for their wide applications in building strategies for advantageously controlled biological applications. The classification of polymers is based on their sources of origin. Nanohydrogel studies are based on their polymeric types and their endorsed utilization for reported applications. Nanotechnology has developed significantly in the past decades. The novel and active role of nano biomaterials with amplified aspects are consistently being studied to minimize the deleterious practices and side effects. Here, we put forth challenges and discuss the outlook regarding the role of nanohydrogels, with future perspectives on delivering constructive strategies and overcoming the critical objectives in nanotherapeutic systems.
Highlights
Nanotechnology has been emerging as a field with high applicability at the nanosize scale, which has driven the concerns of researchers concerning the designing of nanocomposites, nanomaterial, nanocomplex, and nanoscale- based drug carriers [1,2,3]
Studies have proposed that delivery systems must carry therapeutics through the vasculature without any leakage for the development of a prominent platform for drug delivery systems [16]
The polymeric networks in strategic design and the classification of natural and synthetic polymers with reported nanohydrogels synthesis studies and applications of nanohydrogels are summarized from a polymeric perspective in this review
Summary
Nanotechnology has been emerging as a field with high applicability at the nanosize scale, which has driven the concerns of researchers concerning the designing of nanocomposites, nanomaterial, nanocomplex, and nanoscale- based drug carriers [1,2,3]. Regardless of these extensive contributions and progressive approaches concerning therapeutic deliveries, numerous difficulties still exist [4,5,6]. Polymeric nanomaterials as building blocks for nanohydrogels, which are highly biocompatible and biodegradable, has been discovered in nanotechnology stream [26]. The role of employing nanohydrogels as a successful probe in biomedical applications, environmental protection, intelligent devices, cell cultures, protein productions, mechanical properties, and future perspectives are discussed
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