Nanographite-assisted matrix solid phase dispersion microextraction of active and toxic compounds from complex food matrices using cyclodextrin aqueous solution as elution solvent.

Abstract

In this study, a cyclodextrin aqueous solution was used as an environmentally friendly eluent to simultaneously extract active and toxic compounds from food matrices with the aid of nanographite-assisted matrix solid phase dispersion microextraction (NG-MSPDM). The NG-MSPDM procedure was optimized by single-factor experiments and response surface methodology to obtain optimum conditions. The proposed method achieved excellent linearity at 0.10-20μg/mL for all target analytes with a coefficient of correction (R2)≥0.9909, limits of detection < 52.01ng/mL, satisfactory reproducibility below 3.21%, and acceptable recoveries of 82.0-112%. To accurately determine the target components in the complex matrix, collision cross-section values of the analytes were obtained using ion mobility quadrupole time-of-flight mass spectrometry (IM-Q-TOF/MS). Results indicated that the NG-MSPDM method successfully achieved the simultaneous extraction of flavonoids and phenoxyacetic herbicides from Alpinia officinarum.