Abstract

Nanogels are an emerging class of nanomaterials that have shown great potential for biomedical applications, particularly in the field of tissue engineering and regenerative medicine. Nanogel-based scaffolds are promising due to their unique properties, such as high water content, biocompatibility, and tunable drug release. This review article provides an overview of the current state-of-the-art in nanogel-based scaffolds, including their synthesis and characterization, properties, applications in tissue engineering and regenerative medicine, challenges and limitations, and future directions. The synthesis of nanogels is discussed, along with the various methods used for their characterization, such as size and zeta potential measurements, microscopy, and spectroscopy. The unique properties of nanogel-based scaffolds, such as their high water content and tunable drug release, are also discussed in detail. The review article highlights the applications of nanogel-based scaffolds in tissue engineering and regenerative medicine, including their use in wound healing, bone regeneration, and drug delivery. Additionally, the challenges and limitations of nanogel-based scaffolds are discussed, along with future directions for research in this exciting field. Overall, this review article provides a comprehensive overview of the current state-of-the-art in nanogel-based scaffolds, highlighting their potential for future biomedical applications.

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