Abstract
In the recent years, nanomedicine research drives to the designing of multifunctional nanoparticles for various biomedical applications in the field of diagnosis, treatment, and therapy. In particular, the functionalized magnetic nanoparticles (MNPs) have been widely exploited for several advantages which opens up many opportunities in the biomedicine and biotechnology field [1]. It is due to their uncommon chemical and physical features such as magnetic, electronic, and optical properties. And also, MNPs size, shape, surface modification, water dispersity, biocompatibility plays a major role in various applications. Some of the MNPs-based applications are magnetic resonance imaging (MRI), hyperthermia, and drug delivery [2–8]. The extensive studies has been carried out using iron oxides, but among ferrites manganese ferrite (Mf) is prominently used for various biomedical applications which is due to their property such as superparamagnetism, stability, and high magnetization. These properties have attracted the researchers to develop the Mf into multifunctional nanoparticles by various strategies such as core-shell (CSNPs) formation/bimetallic nanoparticles and surface modifications.
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