Nanofat in Facial Rejuvenation

Abstract

Several reports have been published wherein intradermal filling with nanofat has been used for skin rejuvenation, texture improvement and scar treatment. A study was conducted between August 2017 and August 2018 which included 20 female patients having wrinkles, hyperpigmentation, erythema, and enlarged pores. Lidocaine cream, local infiltration with lidocaine or sedation was used in accordance with the patient’s convenience. Nanofat was injected intradermally in all the facial regions. All patients filled a questionnaire at sixth month post treatment which consisted of questions regarding pain, bumps area and resolution, grade of improvement of skin (wrinkles, smoothness, wrinkles, pores and redness), recovery of donor area, time to reincorporate to normal routine, nanofat-time efficacy and recommendation of the treatment. Patients undergoing it with sedation had less bruising and pain. Lateral thigh as the donor area had less pain in the recovery period. The residual bumps persisted for more time in non-mobile areas while average time to disappear was 3.6 weeks. Patients started to notice the change after nanofat injections at about 1.12 months later. The improvement was noticed for smoothness of skin (100% patients), wrinkles (40% patients), pore size reduction (15% patients), improvement in redness (10% patients). The effect of nanofat was felt by patients for an average time of 3.85 months. All the patients were satisfied and recommended it. No major complications were reported. Nanofat treatment is safe and it conveys beneficial effects on skin rejuvenation as per the post-operative skin texture changes and the satisfaction of patients.