Abstract
Emulsions are two-phase mixtures of insoluble liquids in which a “continuous phase” surrounds discrete vesicles of the “dispersed phase”. Nanoemulsions or mini-emulsions or ultrafine emulsions or submicron emulsions are transparent or translucent oil-in-water (o/w) or water-in-oil droplets with a mean droplet diameter in the range between 100 and 500 nm. Nanoemulsion-based delivery system is superior to conventional topical dosage forms, such as ointment and gels, in several respects. Nanoemulsions are composed of safe, well-characterized ingredients, combined in a proprietary manner to yield stable emulsion. Cancer is a class of disorders characterized by abnormal growth of cells proliferating in an uncontrolled way.The efficiency of anticancer drugs is limited by their unsatisfactory properties, such as poor solubility, narrow therapeutic window, and intensive cytotoxicity to normal tissues, which may be the causes of treatment failure in cancer. Nanoemulsions increase the solubility of drugs exhibiting poor water solubility through entrapment in the core of the nanoemulsion droplets. © 2011 IGJPS. All rights reserved.
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