Abstract
The dermal absorption potential of a nanocrystalline magnesium oxide (MgO) and titanium dioxide (TiO2) mixture in dermatomed human skin was assessed in vitro using Bronaugh-type flow-through diffusion cells. Nanocrystalline material was applied to the skin surface at a dose rate of 50 mg/cm2 as a dry powder, as a water suspension, and as a water/surfactant (sodium lauryl sulfate) suspension, for 8 hours. Dermal absorption of nanocrystalline MgO and TiO2 through human skin with intact, functional stratum corneum was not detectable under the conditions of this experiment.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have