Abstract
Experimental results have been presented on studying optical properties of nanoconstructions formed of orientationally ordered neighbouring double-stranded DNA molecules in the structure of their liquid-crystalline phases and dispersion particles of these phases including ones cured with intercalators.
Highlights
The results of calculation of the optical activity of the ds DNA cholesteric liquid-crystalline dispersion (CLCD) particles, carried out in [2], based on the theory of electromagnetic waves absorption with large molecular systems in the model, when the particle is regarded as a set of cells containing a large amount of absorbing radiation chromophores and representing a single complex with a specific, changing the spiral direction of the polarizability, allowed to determine the value of the "structural" circular dichroism of DNA CLCD particles and its dependence on various physical parameters, and most importantly – allowed to come to the conclusion, according to which the formation of a spatially ordered CLCD particles structure must inevitably be accompanied by the appearance of an intense band in the CD spectrum
Applied in [2] approach has been used to study the features of the CD spectra of DNA CLCD treated with some colored biologically active compounds (BAC), which can intercalated between pairs of DNA nitrogen bases and turn out to be included in the threedimensional structure of DNA CLCD particles
Design data were compared with the experimental results obtained by studying the influence of various factors on the DNA CLCD particles including BAC interacting with ds DNA
Summary
The results of calculation of the optical activity of the ds DNA CLCD particles, carried out in [2], based on the theory of electromagnetic waves absorption with large molecular systems in the model, when the particle is regarded as a set of cells containing a large amount of absorbing radiation chromophores (nitrogen bases of DNA) and representing a single complex with a specific, changing the spiral direction of the polarizability, allowed to determine the value of the "structural" circular dichroism of DNA CLCD particles and its dependence on various physical parameters (a step of helical twist of "quasinematic" layers of neighboring DNA molecules, the particle size, and other parameters), and most importantly – allowed to come to the conclusion, according to which the formation of a spatially ordered CLCD particles structure must inevitably be accompanied by the appearance of an intense band in the CD spectrum. Applied in [2] approach has been used to study the features of the CD spectra of DNA CLCD treated with some colored biologically active compounds (BAC), which can intercalated between pairs of DNA nitrogen bases and turn out to be included in the threedimensional structure of DNA CLCD particles.
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