Abstract

A type of novel nanocomposite was successfully synthesized by embedding glutathione capped CdTe/ZnS QDs into sodium alginate biopolymer. The prepared nanocomposite was characterized using transmission electron microscopy (TEM), thermogravimetric analysis (TGA), and Fourier transform infrared (FT-IR), fluorescence, and UV–vis spectroscopy. When the obtained nanocomposite interacted with amantadine, its fluorescence intensity was effectively quenched. Under the optimized conditions, the as-prepared nanocomposite provided an efficient platform for detection of amantadine drug within a linear range of 3.1–27.9 × 10−6 mol/L with a detection limit of 0.09 × 10−6 mol/L. Because of the satisfactory results for amantadine determination in real samples, it is confirmed that the synthesized nanocomposite is attractive and reliable for use in biological detection and related fields.

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