Nano-Based Drug Delivery System in Breast Cancer Treatment

Abstract

Breast cancer is a malignant tumor that seriously endangers women’s health worldwide and is the number one cancer in terms of incidence. In recent years, although the research on interdisciplinary drug delivery systems that combine nanotechnology and medical oncology is fully developed with significant efficacy, such as nano-based drug delivery systems (NDDs), the current clinical translation rate of drug delivery systems is not high. Moreover, NDDs are designed as carrier systems for drug delivery to targets, prolonging drug circulation time in vivo, improving targeting, reducing tumor resistance, and providing new avenues for the prevention and treatment of many diseases. Herein, the current approaches of several commonly used carrier nanoparticles are discussed, mainly including liposomes, polymeric micelles, metals, inorganic nanoparticles and nanohydrogels, as well as composite NDDS in breast cancer treatment, including their properties, system design, major innovations, and applications in clinical settings.