Namık Kemal Üniversitesi Araştırma ve Uygulama Hastanesi'ne başvuran çocuklarda idrar örneklerinden izole edilen etkenler ve antibiyotik direnç durumları

Abstract

Aim. Urinary tract infections are the most common infections in childhood. Antimicrobial resistance has become a serious problem as a result of extensive antibiotic comsumption. In this study determining the bacteria grown in urine cultures of children and antimicrobial resistance rates in our region, was aimed. Methods. Urine samples of children who attended the Namik Kemal University Research and Practice Hospital were inoculated blood and eozin metilen blue agar plates. Isolates were identified by conventional and/or semi automated methods and antibiotic resistance rates were determined according to the recommendations of CLSI. Results. Of the 1003 samples sent, growth was obtained in 127(12.7%).The isolates were as follows; Escherichia coli: 66 (52.0%), coagulase negative staphyococci: 14 (11.0%), Enterococcus spp: 14 11.0(%), Proteus spp: 10 7.9(%), Citrobacter spp:7(5.5%), Klebsiella spp 7 (5,5%), Pseudomonas spp 6(4.7%), Enterobacter spp:1(0.8%) MRSA: 1 0.8(%), and Morganella morganii: 1 (0.8%). The highest resistance rates of Gram negative bacteria had higher resistant to ampicilin (65.2%). Coagulase negative staphylococci and enterococci had higher resistant to erithromycine (respectively 64.3%, and 85.7%). Conclusion. The results of our study showed that, in infections caused by Gram negative bacteria imipenem and amikacin, from oral preparats nitrofurantoin and amoksisilin/clavulanate and in infections caused by Gram positive bacteria teichoplanin and linezolide are the agents that can be used in therapy. Knowledge of the regional resistance patterns can lead the selection of appropriate antibiotic in empiric therapy and as a result of this, management problems, financial problems and the development of antimicrobial resistance can be prevented.