Abstract
A 46-year-old woman was treated for unexplained coma with intravenous lactated Ringer's solution, intravenous glucose, and a gastric lavage. During therapy respiratory depression progressed to apnea. Naloxone hydrochloride was administered intravenously, in three doses, each of 0.4 mg, over a period of ten minutes. Normal breathing and a lightening of coma occurred within minutes, and consciousness returned within four hours. Laboratory studies on blood, urine and lavage returns confirmed the history of ingestion of barbiturate, diazepam and alcohol. No narcotics were detected.
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