N-alkylation of nitriles with tricarbonylchromium complexes of benzyl and related alcohols as synthetic intermediates. Further development of the Ritter reactions

Abstract

The in situ generation of various carbenium ions temporarily stabilized by an organometallic unit situated in the α-position, in the presence of nitriles has allowed the ready preparation of amides in high yields even from primary alcohol precursors, thus extending the scope of the Ritter reaction.