Abstract
Three new sesquiterpenoid quinones, nakijiquinones G–I ( 1– 3), containing a different amino group derived from amino acids have been isolated from Okinawan marine sponges of the family Spongiidae, and the structures and relative stereochemistry of 1– 3 were elucidated on the basis of the spectral data. Nakijiquinones G–I ( 1– 3) showed modest cytotoxicity and inhibitory activity against HER2 kinase, while nakijiquinone H ( 2) exhibited antimicrobial activity.
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