Abstract

Na2S2O8-mediated tandem one-pot construction of 3,3-disubstituted 3,4-dihydroquinoxalin-2(1H)-ones containing a quaternary carbon center from easily accessible 1,2-diaminobenzenes, α-ketoesters and 4-alkyl-1,4-dihydropyridines mediated has been developed. This mild transformation affords the desired products in high yields with ample substrate scope, high compatibility of functional groups and easy scale-up.

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